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Dom └Experimental Approaches to Studying the Complement System in Neuroscience └Chapter 1- Experimental Models for Complement Research in the Nervous System (1)

Experimental Approaches to Studying the Complement System in Neuroscience

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Chapter 1- Experimental Models for Complement Research in the Nervous System (1)

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1. Which complement protein is central to all three activation pathways in the CNS?
a) C1q b) C3 c) C4b d) C4BP
2. What is the primary role of C4b-binding protein (C4BP) in the nervous system?
a) Initiating complement activation b) Regulating complement activity to prevent damage c) Tagging synapses for elimination d) Promoting amyloid aggregation
3. Which in vitro model provides the most patient-specific information on complement function?
a) Primary rodent microglia b) Human iPSC-derived neurons c) Murine astrocyte cultures d) Transgenic mouse lines